N-Acetyl Selank (N-Acetyl Selank Amidate) is a stabilized version of Selank, a synthetic peptide developed in Russia as an anxiolytic and nootropic. Standard Selank is derived from the endogenous immunomodulatory peptide tuftsin, with additional amino acids that shift its effects toward the nervous system.

The N-acetyl and amide modifications in N-Acetyl Selank improve stability by protecting the peptide from enzymatic degradation at both termini. This makes it more practical for research applications, particularly intranasal administration where unmodified peptides can degrade before absorption.

Like standard Selank, N-Acetyl Selank’s primary effects are anxiolytic—reducing anxiety without sedation. It also supports cognitive function, making it popular in the nootropic research community alongside NA-Semax Amidate. The two peptides are often used together for balanced enhancement: NA-Semax for stimulation and focus, N-Acetyl Selank for calm and stress reduction.