Description
SLU-PP-332 is a synthetic compound, not a natural peptide, that acts as a potent agonist for Estrogen-Related Receptors (ERRs), mimicking the effects of aerobic exercise by boosting metabolism, increasing fat burning, and improving endurance in animal models, showing promise for treating metabolic syndrome, obesity, and enhancing muscle function, but it’s still a research chemical for studying these pathways.
What it is & How it works
A Pan-ERR Agonist: SLU-PP-332 activates all three ERR subtypes (α, β, γ), which are crucial regulators of energy metabolism.
Mimics Exercise: It triggers a metabolic state similar to intense aerobic exercise, increasing energy expenditure and fatty acid oxidation (burning fat for fuel).
Key effects observed in studies (mostly mice)
Metabolic Improvement: Decreases body fat, improves insulin sensitivity, and lowers cholesterol/triglycerides in obese models.
Enhanced Muscle Function: Increases mitochondrial respiration, muscle endurance (running distance/time), and strength.
Kidney Protection: Shows potential in inhibiting age-related kidney dysfunction